LSBio
PathPlus™ ESRRA / ERR Alpha Antibody (Internal)

Anti-ESRRA antibody IHC of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PathPlus™ ESRRA / ERR Alpha Antibody (Internal)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Bovine, Dog, Hamster, Horse, Human, Mammal (Other), Mouse, Non-Human Primate, Pig, Rat
Format:Liquid
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$403.00each
Catalog Number: LS-A5402-50

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Overview

Description
ERR Alpha antibody LS-A5402 is an unconjugated rabbit polyclonal antibody to ERR Alpha (ESRRA) (Internal) from human. It is reactive with human, mouse, rat and other species. Validated for ChrIP and IHC. Cited in 5 publications.
Application
IHC
Reactivity
Bov, Can, Ham, Hr, Hu, Mml, Ms, NHP, Por, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ERR Alpha/NR3B1 | ERRa | ERR1 | ESRRA | HERR1 | NR3B1 | Steroid hormone receptor ERR1 | ERR-alpha | ERRalpha | ESRL1 | Estrogen receptor-like 1
Recommended Dilution: IHC-P
8 - 24 µg/ml
UniProt Number
P11474
SwissProt
P11474

Target

Target
ESRRA / ERR Alpha
Antigen Species
Human
Specificity
Human ESRRA. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Epitope
Human ESRRA. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
ESRRA

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 15 amino acid peptide from internal region of human ESRRA. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Bat, Dog, Horse, Pig (100%); Gibbon (93%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Receptor interacting protein 140 regulates expression of uncoupling protein 1 in adipocytes through specific peroxisome proliferator activated receptor isoforms and estrogen-related receptor alpha. Debevec D, Christian M, Morganstein D, Seth A, Herzog B, Parker M, White R. Molecular endocrinology (Baltimore, Md.). 2007;21:1581-92.

PubMed: 17456798 · PMC: PMC2072047


Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression. Morganstein DL, Wu P, Mane MR, Fisk NM, White R, Parker MG. Cell Research. 2010;20:434-44.

PubMed: 20101261 · PMC: PMC2848839


RIP140 expression is stimulated by estrogen-related receptor alpha during adipogenesis. Nichol D, Christian M, Steel JH, White R, Parker MG. The Journal of biological chemistry. 2006 Oct;281:32140-7.

PubMed: 16923809


In vivo antral follicle wall biopsy: a new research technique to study ovarian function at the cellular and molecular levels. Ishak GM, Bashir ST, Dutra GA, Gastal GDA, Gastal MO, Cavinder CA, Feugang JM, Gastal EL. Reproductive biology and endocrinology : RB&E. 2018 July;16:71.

PubMed: 30055625 · PMC: PMC6064614


Transition to the ovulatory season in mares: An investigation of antral follicle receptor gene expression in vivo. Ghassan M A Ishak, Gabriel A Dutra, Gustavo D A Gastal, Melba O Gastal, Jean M Feugang, Eduardo L Gastal. Molecular reproduction and development. 2019 December;86:1832-1845.

PubMed: 31571308

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