LSBio
PathPlus™ CLDN1 / Claudin 1 Antibody (aa162-211)

Anti-CLDN1 / Claudin 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

PathPlus™ CLDN1 / Claudin 1 Antibody (aa162-211)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
See all CLDN1 / Claudin 1 antibodies →
$470.00each
Catalog Number: LS-B6327-50

For bulk orders or custom formulations:

Request a Quote

Overview

Description
Claudin 1 antibody LS-B6327 is an unconjugated rabbit polyclonal antibody to Claudin 1 (CLDN1) (aa162-211) from human. It is reactive with human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Cited in 4 publications.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CLDN1 | Claudin-1 | Claudin 1 | ILVASC | SEMP1 | CLD1
Recommended Dilution: IHC-P
1:200
Recommended Dilution: WB
1:500 - 1:1000
UniProt Number
O95832
SwissProt
O95832

Target

Target
CLDN1 / Claudin 1
Antigen Species
Human
Specificity
Claudin 1 Antibody detects endogenous levels of total Claudin 1 protein.
Epitope
Claudin 1 Antibody detects endogenous levels of total Claudin 1 protein.
Gene Name
CLDN1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from human Claudin 1. (AA Range: 162-211)
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Concentration
1 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS, 150 mM NaCl

Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium. Chen H, Hu Y, Fang Y, Djukic Z, Yamamoto M, Shaheen NJ, Orlando RC, Chen X. Gut. 2014 May;63:711-9.

PubMed: 23676441 · PMC: PMC3883925


Gastroesophageal reflux activates the NF- kappa B pathway and impairs esophageal barrier function in mice. Fang Y, Chen H, Hu Y, Djukic Z, Tevebaugh W, Shaheen NJ, Orlando RC, Hu J, Chen X. American journal of physiology. Gastrointestinal and liver physiology. 2013 Jul;305:G58-65.

PubMed: 23639809 · PMC: PMC3725692


Deeply located low-grade fibromyxoid sarcoma with FUS-CREB3L2 gene fusion in a 5-year-old boy with review of literature. Kurisaki-Arakawa A, Suehara Y, Arakawa A, Takagi T, Takahashi M, Mitani K, Kaneko K, Yao T, Saito T. Diagnostic pathology. 2014;9:163.

PubMed: 25183312 · PMC: PMC4167136


Indol-3-Carbinol and Quercetin Ameliorate Chronic DSS-Induced Colitis in C57BL/6 Mice by AhR-Mediated Anti-Inflammatory Mechanisms. Sina Riemschneider, Maximilian Hoffmann, Ulla Slanina, Klaus Weber, Sunna Hauschildt, Jörg Lehmann. International journal of environmental research and public health. 2021 Feb;18:2262.

PubMed: 33668818 · PMC: PMC7956562

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.