LSBio
PathPlus™ CHGA / Chromogranin A Antibody (clone CHGA/1773R)

Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ CHGA / Chromogranin A Antibody (clone CHGA/1773R)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all CHGA / Chromogranin A antibodies →
$536.00each
Catalog Number: LS-B16273-100

For bulk orders or custom formulations:

Request a Quote

Overview

Description
Chromogranin A antibody LS-B16273 is an unconjugated rabbit recombinant monoclonal antibody to human Chromogranin A (CHGA). Validated for IHC.
Application
IHC
Reactivity
Hu
Nonreactive Species
Rat
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
Chromogranin A | Chromogranin-A | Pancreastatin | Pituitary secretory protein I | Vasostatin I | SP-I | CHGA | Vasostatin II
Recommended Dilution: IHC-P
1:100
UniProt Number
P10645
NCBI GenBank
NM_001275 | NP_001266.1
SwissProt
P10645

Target

Target
CHGA / Chromogranin A
Antigen Species
Human
Specificity
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Epitope
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Gene Name
CHGA

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
CHGA/1773R
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human Chromogranin A (CHGA) protein. Antigen Molecular Weight: 68-75 kDa
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.