CGB / hCG Beta Antibody
Catalog Number: LS-C121620-100
100 µg / $576.00
Antibody: Mouse Monoclonal
Applications: Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation
Reactivity: Human
Format: Lyophilized
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
PathPlus™ CGB / hCG Beta Antibody (clone rHCGb/54)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general) |
| Reactivity: | Human |
| Format: | Liquid |
$536.00each
Catalog Number: LS-B16239-100
Catalog Number: LS-B16239
For bulk orders or custom formulations:
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- Description
- HCG Beta antibody LS-B16239 is an unconjugated mouse recombinant monoclonal antibody to human hCG Beta (CGB). Validated for IHC.
- Application
- IHC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CGB3 | CG-beta | HCGB | hCG Beta | CGB
- Recommended Dilution: IHC-P
- 1:50
- UniProt Number
- Q6NT52
- NCBI GenBank
- NM_000737 | NP_000728.1
- SwissProt
- Q6NT52
Target
- Target
- CGB / hCG Beta
- Antigen Species
- Human
- Specificity
- This MAb reacts with a protein of 22 kDa , identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
- Epitope
- This MAb reacts with a protein of 22 kDa , identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
- Gene Name
- CGB2
Antibody
- Host Species
- Mouse
- Clonality
- Recombinant Monoclonal
- Clone
- rHCGb/54
- Light Chain
- Kappa Light Chain
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human hCG beta protein. Antigen Molecular Weight: 22 kDa
- Immunogen Type
- Full-Length Recombinant Protein
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Animal Free
- No
- Carrier-Free
- No
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS
