CCR4 Antibody
Catalog Number: LS-C743228
2 sizes / from $341.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Anti-CCR4 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PathPlus™ CCR4 Antibody (C-Terminus)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$470.00each
Catalog Number: LS-A351-50
Catalog Number: LS-A351
For bulk orders or custom formulations:
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- Description
- CCR4 antibody LS-A351 is an unconjugated rabbit polyclonal antibody to human CCR4 (C-Terminus). Validated for IHC. Cited in 3 publications.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Predicted Reactivity
- Dog, Non-Human Primate
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- C-C chemokine receptor type 4 | CD194 | CD194 antigen | C-C CKR-4 | Chemr13 | CKR-4 | CC chemokine receptor 4 | CC-CKR-4 | CCR-4 | HGCN:14099 | C-c chemokine receptor 4 | CCR4 | Chemokine (C-C) receptor 4 | CKR4 | CMKBR4 | K5-5 | cc-ckr-4
- Recommended Dilution: IHC-P
- 5 - 10 µg/ml
- UniProt Number
- P51679
- NCBI GenBank
- NM_005508 | NP_005499.1
- SwissProt
- P51679
Target
- Target
- CCR4
- Antigen Species
- Human
- Specificity
- Human CCR4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Epitope
- Human CCR4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Gene Name
- CCR4
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- Synthetic 18 amino acid peptide from C-Terminus of human CCR4. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Panda, Dog (94%); Hamster, Elephant, Bovine, Horse (89%); Bat, Rabbit, Opossum (83%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.1% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Aberrant expression of chemokine receptor CCR4 in human gastric cancer contributes to tumor-induced immunosuppression. Yang YM, Feng AL, Zhou CJ, Liang XH, Mao HT, Deng BP, Yan S, Sun JT, Du LT, Liu J, Wang QJ, Neckenig MR, Yang QF, Qu X. Cancer science. 2011 Jul;102:1264-71.
PubMed: 21443538
Aberrant CCR4 expression is involved in tumor invasion of lymph node-negative human gastric cancer. Yang Y, Du L, Yang X, Qu A, Zhang X, Zhou C, Wang C. PloS one. 2015;10:e0120059.
PubMed: 25790118 · PMC: PMC4366399
CCR4 Expression Is Associated With Poor Prognosis in Patients With Early Stage (pN0) Oral Tongue Cancer. Lei Wang, Mei Zhang, Yuntao Zhu, Xin Zhang, Yongmei Yang, Chuanxin Wang. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 2019 Feb;77:426-432.
PubMed: 30395826
