LSBio
PathPlus™ Alpha-1-Antichymotrypsin Antibody (aa254-303)

Anti-SERPINA3 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PathPlus™ Alpha-1-Antichymotrypsin Antibody (aa254-303)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$470.00each
Catalog Number: LS-B5826-50

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Overview

Description
Alpha-1-Antichymotrypsin antibody LS-B5826 is an unconjugated rabbit polyclonal antibody to human Alpha-1-Antichymotrypsin (aa254-303). Validated for IHC and WB. Cited in 1 publication.
Application
IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Alpha-1-antichymotrypsin | AACT | GIG25 | Growth-inhibiting protein 25 | GIG24 | Serpin A3 | Growth-inhibiting protein 24 | SERPINA3 | a-1-ACT
Recommended Dilution: IHC-P
2.5 µg/ml
Recommended Dilution: WB
0.2 - 1 µg/ml
UniProt Number
P01011
SwissProt
P01011

Target

Target
Alpha-1-Antichymotrypsin
Antigen Species
Human
Specificity
Human SERPINA3
Epitope
Human SERPINA3 isoform 1
Gene Name
SERPINA3

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide located between aa254-303 of human SERPINA3 (P01011, NP_001076). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Mouse, Rat, Hamster (100%); Galago, Marmoset (84%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS
Search for novel STAT3-dependent genes reveals SERPINA3 as a new STAT3 target that regulates invasion of human melanoma cells. Dorota W Kulesza, Kavita Ramji, Marta Maleszewska, Jakub Mieczkowski, Michal Dabrowski, Salem Chouaib, Bozena Kaminska. Laboratory investigation; a journal of technical methods and pathology. 2019 November;99:1607-1621. PubMed: 31278347

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