LSBio
PathPlus™ ADRB3 Antibody (N-Terminus)

Anti-ADRB3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PathPlus™ ADRB3 Antibody (N-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human, Rat
Format:Liquid
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$449.00each
Catalog Number: LS-A4198-50

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Overview

Description
ADRB3 antibody LS-A4198 is an unconjugated rabbit polyclonal antibody to ADRB3 (N-Terminus) from human. It is reactive with human and rat. Validated for ICC and IHC. Cited in 6 publications.
Application
IHC
Reactivity
Hu, Rt
Predicted Reactivity
Guinea Pig
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ADRB3 | Adrenoceptor beta 3 | ADRB3R | Adrenaline beta 3 receptor | Adrenergic, beta-3-, receptor | Beta-3 adrenergic receptor | B3AR | Beta-3 adrenoceptor | Beta3-AR | Beta-3 adrenoreceptor | BETA3AR
Recommended Dilution: IHC-P
10 - 15 µg/ml
UniProt Number
P13945
SwissProt
P13945

Target

Target
ADRB3
Antigen Species
Human
Specificity
N-terminus if human, gorilla ADRB3. BLAST analysis of the peptide immunogen showed no homology with other human proteins
Epitope
Human ADRB3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
ADRB3

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 20 amino acid peptide from N-Terminus extracellular domain of human ADRB3. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (95%); Guinea pig (90%); Monkey, Elephant, Rabbit (85%); Sheep, Goat, Hamster, Cat, Bovine, Horse (80%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Effects of beta3-adrenergic receptor activation on rat urinary bladder hyperactivity induced by ovariectomy. Kullmann FA, Limberg BJ, Artim DE, Shah M, Downs TR, Contract D, Wos J, Rosenbaum JS, de Groat WC. The Journal of pharmacology and experimental therapeutics. 2009;330:704-17.

PubMed: 19515967 · PMC: PMC2729793


Urothelial beta-3 adrenergic receptors in the rat bladder. Kullmann FA, Downs TR, Artim DE, Limberg BJ, Shah M, Contract D, de Groat WC, Rosenbaum JS. Neurourology and urodynamics. 2011;30:144-50.

PubMed: 21046653 · PMC: PMC3395322


Expression and functional role of beta 3 -adrenoceptors in the human ureter. Matsumoto R, Otsuka A, Suzuki T, Shinbo H, Mizuno T, Kurita Y, Mugiya S, Ozono S. International journal of urology : official journal of the Japanese Urological Association. Oct;20:1007-14.

PubMed: 23360304


The expression of ß3-adrenoceptors and their function in the human prostate. Takahisa Suzuki, Atsushi Otsuka, Rikiya Matsumoto, Hiroshi Furuse, Seiichiro Ozono. The Prostate. 2016 Feburary;76:163-71.

PubMed: 26768278


Beta-3 adrenergic receptor is expressed in acetylcholine-containing nerve fibers of the human urinary bladder: An immunohistochemical study. Ana Coelho, Tiago Antunes-Lopes, James Gillespie, Francisco Cruz. Neurourology and urodynamics. 2017 November;36:1972-1980.

PubMed: 28185314

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