Positive WB detected in:Mouse brain tissue,Mouse kidney tissue,Mouse liver tissue,Rat lung tissue,Rat skeletal muscle tissue;All lanes:P2RX4 antibody at 3?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 44,46,41 KDa;Observed band size: 44 KDa;
P2RX4 / P2X4 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C501672-50
Catalog Number: LS-C501672
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- Description
- P2X4 antibody LS-C501672 is an unconjugated rabbit polyclonal antibody to P2X4 (P2RX4) from human. It is reactive with human, mouse and rat. Validated for ELISA, IHC and WB. Cited in 1 publication.
- Application
- ELISA, IHC, IHC-P, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- ATP receptor | p2X purinoceptor 4 | p2X4R | p2RX4 | p2X receptor 4 | p2X4 | p2X4 purinoceptor | Purinergic receptor P2X4 | Purinoceptor P2X4 | Purinergic receptor | p2X receptor, subunit 4
- Recommended Dilution: IHC-P
- 10 µg/ml
- UniProt Number
- Q99571
- NCBI GenBank
- NM_002560 | NP_002551.2
- SwissProt
- Q99571
Target
- Target
- Human P2RX4 / P2X4
- Antigen Species
- Human
- Epitope
- Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.
- Gene Name
- P2RX4
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human P2X purinoceptor 4 protein (91-176AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Concentration
- 3 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells. Cody L Dunton, J Todd Purves, Francis M Hughes Jr, Huixia Jin, Jiro Nagatomi. International urology and nephrology. 2018 September;50:1607-1617. PubMed: 30099658 PMC: PMC6129973