LSBio
OPTN / Optineurin Antibody

Western blot analysis of extracts of various cell lines.

OPTN / Optineurin Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all Human OPTN / Optineurin antibodies →
$281.00each
Catalog Number: LS-C331724-20

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Overview

Description
Optineurin antibody LS-C331724 is an unconjugated rabbit polyclonal antibody to Optineurin (OPTN) from human. It is reactive with human and mouse. Validated for IHC and WB. Cited in 1 publication.
Application
IHC, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ALS12 | E3-14.7K-interacting protein | FIP-2 | HIP-7 | HYPL | Huntingtin yeast partner L | HIP7 | TFIIIA-INTP | NEMO-related protein | NRP | Optineurin | OPTN | FIP2 | GLC1E
Recommended Dilution: IHC
1:50 - 1:200
Recommended Dilution: WB
1:500 - 1:2000
UniProt Number
Q96CV9
SwissProt
Q96CV9

Target

Target
Human OPTN / Optineurin
Antigen Species
Human
Epitope
Human OPTN / Optineurin
Gene Name
OPTN

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-577 of human OPTN (NP_068815.2). MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKLNNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSERSSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVEIRMAEGEAEGSVKEIKHSPGPTRTVSTGTALSKYRSRSADGAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLT
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol
Volume
20 Microliter
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. Jun Araya, Kazuya Tsubouchi, Nahoko Sato, Saburo Ito, Shunsuke Minagawa, Hiromichi Hara, Yusuke Hosaka, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Masahiro Yoshida, Yu Fujita, Hirofumi Utsumi, Kenji Kobayashi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Takeo Ishikawa, Takanori Numata, Yumi Kaneko, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Toshiaki Morikawa, Stephen L Nishimura, Katsutoshi Nakayama, Kazuyoshi Kuwano. Autophagy. 2018 October;42736. PubMed: 30290714 PMC: PMC6351145

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