Western Blot analysis of NUDT1 expression in transfected 293T cell line by NUDT1 monoclonal antibody (M02), clone 5F11.Lane 1: NUDT1 transfected lysate(18 KDa).Lane 2: Non-transfected lysate.
NUDT1 / MTH1 Antibody (clone 5F11)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$342.00each
Catalog Number: LS-C197715-100
Catalog Number: LS-C197715
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- Description
- MTH1 antibody LS-C197715 is an unconjugated mouse monoclonal antibody to human MTH1 (NUDT1). Validated for ELISA and WB. Cited in 1 publication.
- Application
- ELISA, IHC, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- 8-oxo-dGTPase | 2-hydroxy-dATP diphosphatase | MutT human homolog 1 | Nudix motif 1 | NUDT1 | MTH1
- UniProt Number
- P36639
- NCBI GenBank
- NM_002452 | NP_002443.3
- SwissProt
- P36639
Target
- Target
- Human NUDT1 / MTH1
- Antigen Species
- Human
- Epitope
- Human NUDT1 / MTH1
- Gene Name
- NUDT1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 5F11
- Isotype
- IgG2a
- Light Chain
- Kappa Light Chain
Immunogen
- Immunogen
- NUDT1 (AAH14618, aa 1-179). A full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Immunogen Type
- Fusion Protein (e.g., GST, MBP tag)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4
- Preservative
- No
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Glioblastoma and glioblastoma stem cells are dependent on functional MTH1. Pudelko L, Rouhi P, Sanjiv K, Gad H, Kalderén C, Höglund A, Squatrito M, Schuhmacher AJ, Edwards S, Hägerstrand D, Berglund UW, Helleday T, Bräutigam L. Oncotarget. 2017 July;8:84671-84684. PubMed: 29156675 PMC: PMC5689565