Positive WB detected in:Mouse brain tissue;All lanes: THAP7 antibody at 3ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 35 kDa;Observed band size: 35 kDa;
NPL / C112 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C501846-50
Catalog Number: LS-C501846
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- Description
- C112 antibody LS-C501846 is an unconjugated rabbit polyclonal antibody to C112 (NPL) from human. It is reactive with human and mouse. Validated for ELISA, IF and WB.
- Application
- ELISA, IF, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- C1orf13 | NPL | Sialic acid lyase | Sialate-pyruvate lyase | N-acetylneuraminate lyase | NAL | Sialate lyase | Sialic acid aldolase | C112 | DHDPS1 | NALase | NPL1
- UniProt Number
- Q9BXD5
- NCBI GenBank
- NM_030769 | NP_110396.1
- SwissProt
- Q9BXD5
Target
- Target
- Human NPL / C112
- Antigen Species
- Human
- Epitope
- Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (By similarity).
- Gene Name
- NPL
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human N-acetylneuraminate lyase protein (17-77AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS