LSBio
NOX4 Antibody (aa561-578)

WB of NOX4 antibody. Lane 1: Rat Kidney Tissue Lysate. Lane 2: Rat Cardiac Muscle Tissue Lysate. Lane 3: Rat Spleen Tissue Lysate. Lane 4: HELA Cell Lysate. Lane 5: 293T Cell Lysate. Lane 6: MCF-7 Cell Lysate. Lane 7: SMMC Cell Lysate.

NOX4 Antibody (aa561-578)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Lyophilized
See all Mouse NOX4 antibodies →
$480.00each
Catalog Number: LS-C313066-100

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Overview

Description
NOX4 antibody LS-C313066 is an unconjugated rabbit polyclonal antibody to NOX4 (aa561-578) from mouse. It is reactive with human, mouse and rat. Validated for IHC and WB. Cited in 3 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Kidney oxidase-1 | KOX | RENOX | KOX-1 | NADPH oxidase 4 | NOX4 | Renal NAD(P)H-oxidase
UniProt Number
Q9NPH5
SwissProt
Q9NPH5

Target

Target
Mouse NOX4
Antigen Species
Mouse
Epitope
EXpressed in brain, in all layers of the cerebellum, in pyramidal cells of the Ammon horn and in Purkinje cells (at protein level). Expressed in osteoclasts, leukocytes, kidney, liver and lung. .
Gene Name
NOX4

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
A synthetic peptide corresponding to a sequence at the C-Terminus of mouse NADPH oxidase 4(561-578 aa NRNNSYGTKFEYNKES), identical to the related rat sequence and different from the related human sequence by two amino acids.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg Thimerosal, 0.05mg sodium azide.
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Recommended Storage Buffer
NaCl

Nuclear NADPH oxidase-4 associated with disease progression in renal cell carcinoma. Dharam Kaushik, Keith A Ashcraft, Hanzhang Wang, Karthigayan Shanmugasundaram, Pankil K Shah, Gabriela Gonzalez, Alia Nazarullah, Cooper B Tye, Michael A Liss, Deepak K Pruthi, Ahmed M Mansour, Wasim Chowdhury, Dean Bacich, Hao Zhang, Amanda L Watson, Karen Block, Denise O'Keefe, Ronald Rodriguez. Translational research : the journal of laboratory and clinical medicine. 2020 Sep;;223:44575.

PubMed: 32492552 · PMC: PMC8111697


Effects of anagliptin on the stress induced accelerated senescence of human umbilical vein endothelial cells. Seon Mee Kang , Hye Sook Jung, Min Jeong Kwon, Soon Hee Lee, Jeong Hyun Park. Annals of Translational Medicine. 2021 May;;9:750.

PubMed: 34268363 · PMC: PMC8246235


Role of Nox4 in Mitigating Inflammation and Fibrosis in Dextran Sulfate Sodium-Induced Colitis. Yura Lee, Sung-Hee Kim, Haengdueng Jeong, Kwang H Kim, Donghun Jeon, Yejin Cho, Daekee Lee, Ki Taek Nam. Cellular and molecular gastroenterology and hepatology. 2023 May;16:411-429.

PubMed: 37207801 · PMC: PMC10372905

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