LSBio
NKX6-1 Antibody (aa1-120)

NKX6-1 Antibody (aa1-120)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity:Human, Mouse
Format:Lyophilized
See all Human NKX6-1 antibodies →
$993.00each
Catalog Number: LS-C124275-100

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Overview

Description
NKX6-1 antibody LS-C124275 is an unconjugated goat polyclonal antibody to NKX6-1 (aa1-120) from human. It is reactive with human and mouse. Validated for ELISA, IHC and WB. Cited in 3 publications.
Application
ELISA, IHC, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
NKX6A | NKX6-1 | NK homeobox, family 6, A | NK6 homeobox 1 | Homeobox protein Nkx-6.1 | NKX6.1
Recommended Dilution: ELISA
0.5 - 1 ug/ml
UniProt Number
P78426
SwissProt
P78426

Target

Target
Human NKX6-1
Antigen Species
Human
Epitope
Recognizes human NKX6.1. Species cross-reactivity: mouse.
Gene Name
NKX6-1

Antibody

Host Species
Goat
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
E. coli-derived, recombinant human NKX6.1 (aa 1-120).
Immunogen Type
Recombinant Protein Fragment

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from PBS, pH 7.4, 5% Trehalose
Concentration
0.2 mg/mL
Preservative
No
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at -20°C lyophilized. Once reconstituted: Store at -20°C. Aliquot to avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant ß cells. Blaise Su Jun Low, Chang Siang Lim , Shirley Suet Lee Ding , Yaw Sing Tan , Natasha Hui Jin Ng, Vidhya Gomathi Krishnan, Su Fen Ang, Claire Wen Ying Neo, Chandra S Verma, Shawn Hoon, Su Chi Lim, E Shyong Tai, Adrian Kee Keong Teo. Nature communications. 2021 May;12:3133.

PubMed: 34035238 · PMC: PMC8149827


Differentiation of human pluripotent stem cells into two distinct NKX6.1 populations of pancreatic progenitors. Idil I Aigha, Bushra Memon, Ahmed K Elsayed, Essam M Abdelalim. Stem cell research & therapy. 2018 Apr;9:83.

PubMed: 29615106 · PMC: PMC5883581


Insulin expression and C-peptide in type 1 diabetes subjects implanted with stem cell-derived pancreatic endoderm cells in an encapsulation device. A M James Shapiro, David Thompson, Thomas W Donner, Melena D Bellin, Willa Hsueh, Jeremy Pettus, Jon Wilensky, Mark Daniels, Richard M Wang, Eugene P Brandon, Manasi S Jaiman, Evert J Kroon, Kevin A D'Amour, Howard L Foyt. Cell reports. Medicine. 2021 December;2:100466.

PubMed: 35028608 · PMC: PMC8714853

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