NCR1 / NKP46 Antibody (clone AKS1, Low Endotoxin)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Western Blot |
| Reactivity: | Bovine |
| Format: | Liquid |
$687.00each
Catalog Number: LS-C44750-0.5
Catalog Number: LS-C44750
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- Description
- NKP46 antibody LS-C44750 is an unconjugated mouse monoclonal antibody to bovine NKP46 (NCR1). Validated for Flow, IF and WB.
- Application
- FC, IF, IHC, WB
- Reactivity
- Bov
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD335 | HNKp46 | NCR1 | NK-p46 | Lymphocyte antigen 94 homolog | NK cell-activating receptor | CD335 antigen | LY94 | NKP46
- Recommended Dilution: FC
- 1:5 - 1:200
- UniProt Number
- O76036
- NCBI GenBank
- NM_004829 | NP_004820.2
- SwissProt
- O76036
Target
- Target
- Bovine NCR1 / NKP46
- Antigen Species
- Bovine
- Epitope
- Specific for bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells. The bovine homologue is expressed on bovine NK cells (2) and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells.
- Gene Name
- NCR1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- AKS1
- Isotype
- IgG1
Immunogen
- Immunogen
- Fusion protein consisting of the extracellular region of bovine CD335.
- Immunogen Type
- Fusion Protein (e.g., GST, MBP tag)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS