Immunofluorescent analysis of HepG2 cells using MYD88 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

MYD88 Antibody

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunofluorescence
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C501677-50

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Overview

Description: MYD88 antibody LS-C501677 is an unconjugated rabbit polyclonal antibody to human MYD88. Validated for ELISA and IF.
Application: ELISA, IF
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: MYD88D | MYD88
UniProt Number: Q99836
NCBI GenBank: NM_002468 | NP_002459.2
SwissProt: Q99836

Target

Target: Human MYD88
Antigen Species: Human
Epitope: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
Gene Name: MYD88