Positive WB detected in:A549 whole cell lysate,NIH/3T3 whole cell lysate,Hela whole cell lysate;All lanes: MX1 antibody at 3ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 76,56 kDa;Observed band size: 76 kDa;

MX1 / MX Antibody

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunoprecipitation, Western Blot
Reactivity:	Human, Mouse
Format:	Liquid

$300.00each

Catalog Number: LS-C499388-50

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Overview

Description: MX antibody LS-C499388 is an unconjugated rabbit polyclonal antibody to MX (MX1) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC, IP and WB.
Application: ELISA, IF, IHC, IP, WB
Reactivity: Hu, Ms
Intended Use: RUO
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: Interferon-induced protein p78 | Myxovirus resistance protein 1 | IFI-78K | IFI78 | MX | MX1 | MxA | Myxoma resistance protein 1
UniProt Number: P20591
NCBI GenBank: NM_002462, NP_002453.2
SwissProt: P20591

Target

Target: Human MX1 / MX
Antigen Species: Hu
Epitope: Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.
Gene Name: MX1