SP2/0 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
MtTFA / TFAM Antibody (aa169-218)
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Mouse |
| Format: | Liquid |
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- Description
- TFAM antibody LS-C30495 is an unconjugated rabbit polyclonal antibody to mouse TFAM (MtTFA) (aa169-218). Validated for IHC and WB. Cited in 6 publications.
- Application
- IHC, IHC-P, WB
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- MTTF1 | TFAM | TCF-6 | TCF6 | TCF6L1 | Transcription factor 6-like 2 | Transcription factor 6-like 3 | TCF6L2 | TCF6L3 | Transcription factor 6 | Transcription factor 6-like 1 | MTTFA
- UniProt Number
- Q00059
- NCBI GenBank
- NM_003201 | NP_003192.1
- SwissProt
- Q00059
Target
- Target
- Mouse MtTFA / TFAM
- Antigen Species
- Mouse
- Epitope
- Mouse TFAM
- Gene Name
- TFAM
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Synthetic peptide located between aa169-218 of mouse Tfam (P40630, NP_033386). Percent identity by BLAST analysis: Mouse, Rat (100%); Bat (83%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% sodium azide, 2% sucrose
- Concentration
- 0.5 mg/mL
- Volume
- 100 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
Aging synaptic mitochondria exhibit dynamic proteomic changes while maintaining bioenergetic function. Stauch KL, Purnell PR, Fox HS. Aging. 2014 Apr;6:320-34.
PubMed: 24827396 · PMC: PMC4032798
Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability. Stauch KL, Purnell PR, Fox HS. Journal of proteome research. 2014 May;13:2620-36.
PubMed: 24708184 · PMC: PMC4015687
MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and Forkhead box j3. Yamamoto H, Morino K, Nishio Y, Ugi S, Yoshizaki T, Kashiwagi A, Maegawa H. American journal of physiology. Endocrinology and metabolism. 2012 Dec;303:E1419-27.
PubMed: 23047984
Proteomic analysis and functional characterization of mouse brain mitochondria during aging reveal alterations in energy metabolism. Purnell PR, Villeneuve LM, Fox HS. Proteomics. Dec.
PubMed: 25546256
Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis. Ohashi N, Morino K, Ida S, Sekine O, Lemecha M, Kume S, Park SY, Choi CS, Ugi S, Maegawa H. Diabetes. 2017 September;66:2351-2362.
PubMed: 28637651
MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-a signalling in beige adipocytes. Lemecha M, Morino K, Imamura T, Iwasaki H, Ohashi N, Ida S, Sato D, Sekine O, Ugi S, Maegawa H. Scientific reports. 2018 October;8:15096.
PubMed: 30305668 · PMC: PMC6180067