MSR1 / CD204 Antibody (clone 2F8, FITC)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general) |
| Reactivity: | Mouse |
| Format: | Liquid |
$335.00each
Catalog Number: LS-C43466-0.1
Catalog Number: LS-C43466
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- Description
- CD204 antibody LS-C43466 is an FITC-conjugated rat monoclonal antibody to mouse CD204 (MSR1). Validated for Flow. Cited in 1 publication.
- Application
- FC, IHC
- Reactivity
- Ms
- Intended Use
- RUO
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD204 antigen | MSR1 | SCARA1 | PhSR1 | SR-A | CD204 | PhSR2 | SRA | MSR2
- Recommended Dilution: FC
- 1:10 - 1:50
- UniProt Number
- P21757
- NCBI GenBank
- NM_002445, NP_002436.1
- SwissProt
- P21757
Target
- Target
- Mouse MSR1 / CD204
- Antigen Species
- Ms
- Epitope
- Recognizes the murine scavenger receptor class A (SRA), type I and II, also known as CD204. CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e. g. atherosclerotic lesions. Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion. Recognizes an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.
- Gene Name
- MSR1
Antibody
- Host Species
- Rt
- Clonality
- Monoclonal
- Clone
- 2F8
- Isotype
- IgG2b
Immunogen
- Immunogen
- RAW264 cell line
- Immunogen Type
- Cell
Format
- Conjugate/Label
- FITC
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide, 1% BSA
- Concentration
- 0.1 mg/mL
- Preservative
- Yes
- Purification Method
- Prot G
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store -20°C. Avoid freeze-thaw cycles. Protect from light. Store undiluted.
- Recommended Storage Buffer
- PBS
The phosphodiesterase 4 inhibitor AA6216 suppresses activity of fibrosis-specific macrophages. Takashi Matsuhira , Osamu Nishiyama, Yuji Tabata, Shinji Kurashimo, Hiroyuki Sano, Takashi Iwanaga, Yuji Tohda. Biochemistry and biophysics reports. 2021 Aug;28:101118. PubMed: 34485715 PMC: PMC8408426