Human Apolipoprotein H Antibody (IgG) ELISA Kit (Sandwich ELISA)
Catalog Number: LS-F67372-1
1 plate / $591.00
Reactivity: Human
Detection Method Colorimetric
Format: 96-Well Strip Plate
MSH6 Antibody (clone 44)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunoprecipitation, Western Blot |
| Reactivity: | Dog, Human, Mouse, Rat |
| Format: | Liquid |
$289.00each
Catalog Number: LS-C95606-0.1
Catalog Number: LS-C95606
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- MSH6 antibody LS-C95606 is an unconjugated mouse monoclonal antibody to MSH6 from human. It is reactive with human, mouse, rat and other species. Validated for IP and WB.
- Application
- IP, WB
- Reactivity
- Can, Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- GTBP | HSAP | GTMBP | MutS (E. coli) homolog 6 | HMSH6 | Sperm-associated protein | MSH6 | p160 | G/T mismatch-binding protein | HNPCC5 | MutS homolog 6 (E. coli) | MutS-alpha 160 kDa subunit
- Recommended Dilution: WB
- 1:100 - 1:500
- UniProt Number
- P52701
- NCBI GenBank
- NM_000179 | NP_000170.1
- SwissProt
- P52701
Target
- Target
- Human MSH6
- Antigen Species
- Human
- Epitope
- MSH6 is a heterodimer of MSH2 and binds to DNA containing G/T mismatches. The MSH2-MSH6 complex recognizes a single-based mispair insertion/deletion loop. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related human carcinogenesis. Studies have shown the mutations of MLH-1, MSH2 and MSH6 genes contribute to the development of sporadic colorectal carcinoma. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. cross reacts with mouse, rat and dog.
- Gene Name
- MSH6
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 44
- Isotype
- IgG1
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic human MSH6 peptide.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 0.05% Sodium Azide
- Volume
- 0.1 Milliliter
- Preservative
- Yes
- Purification Method
- Other
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C. Do not freeze.
