LSBio
MPZL1 Antibody

Immunohistochemistry of paraffin-embedded human heart tissue using MPZL1 Antibody at dilution of 1:100

MPZL1 Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all Human MPZL1 antibodies →
$300.00each
Catalog Number: LS-C499346-50

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Overview

Description
MPZL1 antibody LS-C499346 is an unconjugated rabbit polyclonal antibody to human MPZL1. Validated for ELISA, IF and IHC.
Application
ELISA, IF, IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Myelin protein zero-like 1 | MPZL1 | MPZL1b | Protein zero-related | PZR | PZR1b | PZRa | PZRb | Protein zero related
UniProt Number
O95297
SwissProt
O95297

Target

Target
Human MPZL1
Antigen Species
Human
Epitope
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
Gene Name
MPZL1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant human Myelin protein zero-like protein 1 protein (195-258AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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