LSBio
Monoclonal Rat anti-Virus EBV LMP2A Antibody (clone 15F9, IHC, WB)

Monoclonal Rat anti-Virus EBV LMP2A Antibody (clone 15F9, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Immunohistochemistry, Paraffin, Western Blot
Reactivity:Virus / Viral Antigen
Format:Liquid
See all Virus EBV LMP2A antibodies →
$415.00each
Catalog Number: LS-C57991-0.25

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Overview

Description
EBV LMP2A antibody LS-C57991 is an unconjugated rat monoclonal antibody to virus EBV LMP2A. Validated for IHC and WB.
Application
IHC-P, WB
Reactivity
Vir
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: WB
1:100 - 1:1000

Target

Target
Virus EBV LMP2A
Antigen Species
Virus / Viral Antigen
Epitope
Recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. Recognizes LMP2A and does not cross react with LMP2B.

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
15F9
Isotype
IgG1

Immunogen

Immunogen
Bacterial TrpE-LMP2A fusion protein.
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.