Monoclonal Rat anti-Rat BAFF / TNFSF13B Antibody (Biotin)
Catalog Number: LS-C12084-100
100 µg / $943.00
Antibody: Rat Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay, Flow Cytometry
Reactivity: Mouse, Rat
Format: Liquid
TIM-2 transfected NRK cells stained with Rat anti-Mouse TIM-2:FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
Monoclonal Rat anti-Mouse TIMELESS Antibody (clone RMT2-25, FITC)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Flow Cytometry |
| Reactivity: | Mouse |
| Format: | Liquid |
$339.00each
Catalog Number: LS-C187574-0.1
Catalog Number: LS-C187574
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- TIMELESS antibody LS-C187574 is an FITC-conjugated rat monoclonal antibody to mouse TIMELESS. Validated for Flow.
- Application
- FC
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Timeless (Drosophila) homolog | Timeless circadian clock | TIMELESS1 | TIM1 | Protein timeless homolog | HTIM | TIM | TIMELESS | Timeless homolog (Drosophila) | Tof1 homolog
- UniProt Number
- Q9UNS1
- NCBI GenBank
- NM_003920 | NP_003911.2
- SwissProt
- Q9UNS1
Target
- Target
- Mouse TIMELESS
- Antigen Species
- Mouse
- Epitope
- Clone RMT2-25 specifically recognizes mouse Tim-2 (T-cell immunoglobulin mucin 2), a transmembrane glycoprotein and member of the immunoglobulin superfamily, expressed by activated lymphocytes, developmentally in the 8-cell embryo and blastocyst, and preferentially up-regulated in Th2 cells and down-regulated in Th1 cells. Tim-2 acts as a negative regulator of Th2 cells, and is implicated to play a critical role in the development of atopic disease and other Th2-biased immune responses. Tim-2 also acts as a receptor for Semaphorin 4A, a transmembrane protein expressed on dendritic cells and B cells, which plays a role in the guidance of axonal migration during neuronal development, and has been shown to enhance T cell activation. Studies using clone RMT2-25 in mouse, have shown that signaling by Tim-2 can influence the proliferation and antibody production of B cells, during early phase CIA (collagen-induced arthritis) see for details. Clone RMT2-25 has been shown to significantly enhance the proliferation of stimulated splenic B cells in vitro.
- Gene Name
- TIMELESS
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Clone
- RMT2-25
- Isotype
- IgG2a
Format
- Conjugate/Label
- Fluorescein Isothiocyanate
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide, 1% BSA
- Concentration
- 0.1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS
