Monoclonal Rat anti-Rat BAFF / TNFSF13B Antibody (Biotin)
Catalog Number: LS-C12084-100
100 µg / $943.00
Antibody: Rat Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay, Flow Cytometry
Reactivity: Mouse, Rat
Format: Liquid
Monoclonal Rat anti-Mouse ITGAV/Integrin Alpha V/CD51 Antibody (clone RMV-7, IHC)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunoprecipitation |
| Reactivity: | Mouse |
| Format: | Liquid |
$392.00each
Catalog Number: LS-C57970-0.25
Catalog Number: LS-C57970
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- Description
- CD51 antibody LS-C57970 is an unconjugated rat monoclonal antibody to mouse CD51 (ITGAV / Integrin Alpha V). Validated for Flow, IHC and IP. Cited in 2 publications.
- Application
- FC, IHC, IHC-F, IP
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD51 | CD51 antigen | Integrin, alpha V | MSK8 | Integrin Alpha V | Integrin alpha-V | ITGAV | VNRA | Vitronectin receptor | Integrin alphaVbeta3 | VTNR
- Recommended Dilution: FC
- 1:25 - 1:100
- Recommended Dilution: IHC-F
- 1:25 - 1:100
- UniProt Number
- P06756
- NCBI GenBank
- NM_002210 | NP_002201.1
- SwissProt
- P06756
Target
- Target
- Mouse ITGAV/Integrin Alpha V/CD51
- Antigen Species
- Mouse
- Epitope
- Recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 function as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
- Gene Name
- ITGAV
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Clone
- RMV-7
- Isotype
- IgG1
Immunogen
- Immunogen
- Cultured LAK cells from Balb/c mice
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Molecular magnetic resonance imaging of angiogenesis in vivo using polyvalent cyclic RGD-iron oxide microparticle conjugates. Melemenidis S, Jefferson A, Ruparelia N, Akhtar AM, Xie J, Allen D, Hamilton A, Larkin JR, Perez-Balderas F, Smart SC, Muschel RJ, Chen X, Sibson NR, Choudhury RP. Theranostics. 2015;5:515-29.
PubMed: 25767618 · PMC: PMC4350013
Pulmonary pericytes regulate lung morphogenesis. Kato K, Diéguez-Hurtado R, Park DY, Hong SP, Kato-Azuma S, Adams S, Stehling M, Trappmann B, Wrana JL, Koh GY, Adams RH. Nature communications. 2018 June;9:2448.
PubMed: 29934496 · PMC: PMC6015030
