LSBio
Monoclonal Rat anti-Mouse Gr-1 Antigen Antibody (clone RB6-8C5, IHC, IF, WB)

Monoclonal Rat anti-Mouse Gr-1 Antigen Antibody (clone RB6-8C5, IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunoprecipitation, Western Blot
Reactivity:Mouse
Format:Liquid
See all Mouse Gr-1 Antigen antibodies →
$286.00each
Catalog Number: LS-C44779-0.1

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Overview

Description
Gr-1 Antigen antibody LS-C44779 is an unconjugated rat monoclonal antibody to mouse Gr-1 Antigen. Validated for Flow, IF, IHC, IP and WB.
Application
FC, IF, IHC, IHC-F, IP, WB
Reactivity
Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: FC
1:100 - 1:200

Target

Target
Mouse Gr-1 Antigen
Antigen Species
Mouse
Epitope
Recognizes the mouse Gr-1 antigen, a 21-25kD cell surface protein that belongs to the Ly-6 family of proteins. Clone Reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been demonstrated. The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes. Expression of Gr-1 on a subpopulation of lymphocytes has also been reported. Clone RB6-8C5 has been reported to deplete mouse mature neutrophils in vivo. XXX recommend the use of MCA2387EL for functional studies.

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
RB6-8C5
Isotype
IgG2b

Immunogen

Immunogen
Normal murine bone marrow cells
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.