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Monoclonal Rat anti-Mouse CD71 / Transferrin Receptor Antibody (clone 8D3, Low Endotoxin, IHC)

Monoclonal Rat anti-Mouse CD71 / Transferrin Receptor Antibody (clone 8D3, Low Endotoxin, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:Mouse
Format:Liquid
See all Mouse CD71 / Transferrin Receptor antibodies →
$654.00each
Catalog Number: LS-C44905-0.5

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Overview

Description
Transferrin Receptor antibody LS-C44905 is an unconjugated rat monoclonal antibody to mouse Transferrin Receptor (CD71). Validated for Flow and IHC.
Application
FC, IHC, IHC-F
Reactivity
Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD71 | TFR1 | TFRC | TRFR | TFR | TR | CD71 antigen | p90 | T9 | Transferrin receptor | Transferrin receptor protein 1
Recommended Dilution: FC
1:100 - 1:200
UniProt Number
P02786
SwissProt
P02786

Target

Target
Mouse CD71 / Transferrin Receptor
Antigen Species
Mouse
Epitope
Recognizes mouse CD71, a 95kD cell surface protein that is otherwise known as transferrin receptor. CD71 is a major iron-binding protein, which plays a key role in the transport of iron into cells that require it. In mice, CD71 is widely expressed on a variety of cells, including Sertoli cells and cells which form the blood brain barrier (BBB) in the central nervous system. Recognizes native, soluble and denatured forms of murine CD71. Binding of the 8D3 antibody to CD71 does not inhibit the proliferation of cell lines tested, and does not interfere with the uptake of iron into cells. The antibody has been used as a BBB transporter vector in mice and is suitable for studying CD71 expression, and iron uptake into different tissues, in the mouse.
Gene Name
TFRC

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
8D3
Isotype
IgG2a

Immunogen

Immunogen
Mouse transformed endothelioma cell line t. end1.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS
Concentration
1 mg/mL
Preservative
No
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.