LSBio
Monoclonal Rat anti-Mouse CD4 Antibody (clone GK1.5, IHC, IF, WB)

Monoclonal Rat anti-Mouse CD4 Antibody (clone GK1.5, IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Frozen, Immunoprecipitation, Western Blot
Reactivity:Mouse
Format:Liquid
See all Mouse CD4 antibodies →
$392.00each
Catalog Number: LS-C188471-0.25

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Overview

Description
CD4 antibody LS-C188471 is an unconjugated rat monoclonal antibody to mouse CD4. Validated for ELISA, Flow, IF, IHC, IP and WB.
Application
ELISA, FC, IF, IHC-F, IP, WB
Reactivity
Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD4 | CD4 antigen | CD4 receptor | CD4mut | CD4 antigen (p55) | CD4 molecule
Recommended Dilution: FC
1:10 - 1:200
UniProt Number
P01730
SwissProt
P01730

Target

Target
Mouse CD4
Antigen Species
Mouse
Epitope
Recognizes mouse CD4, a 55 kD protein also known as Ly-4 and L3T4. CD4 is a single chain transmembraneous glycoprotein which belongs to the immunoglobulin superfamily, and is primarily expressed on peripheral blood monocytes and tissue macrophages. CD4 is also expressed on a subpopulation of regulatory T cells (CD4+ CD25+), which play a key role in the maintenance of self tolerance. Clone GK1.5 has been reported to block CD4+ T-cell activation. It blocks class II MHC antigen-specific binding, thereby inhibiting functions such as class II MHC antigen-specific proliferation and the release of lymphokines. It may also be used for in vivo and in vitro cell depletion of CD4+ T-cells.
Gene Name
CD4

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
GK1.5
Isotype
IgG2b

Immunogen

Immunogen
Murine CD4.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.