LSBio
Monoclonal Rat anti-Dog CD8 Antibody (clone YCATE55.9, IHC, IF)

Flow cytometry of canine peripheral blood lymphocytes with Rat anti-Dog CD8. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Monoclonal Rat anti-Dog CD8 Antibody (clone YCATE55.9, IHC, IF)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:Dog
Format:Liquid
See all Dog CD8 antibodies →
$363.00each
Catalog Number: LS-C187454-0.1

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Overview

Description
CD8 antibody LS-C187454 is an unconjugated rat monoclonal antibody to dog CD8. Validated for Flow, IF and IHC.
Application
FC, IF, IHC, IHC-F
Reactivity
Can
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies

Target

Target
Dog CD8
Antigen Species
Dog
Epitope
Was clustered as Canine CD8 in the First Canine Leukocyte Antigen Workshop. YCATE55.9 reacts with a rat cell line transfected with cDNA for canine CD8alpha and blocks MHC class I dependant T-cell responses in vitro and in vivo. Has been shown to deplete circulating CD8+ T cells when administered to dogs in vivo. Reduced levels of circulating CD8+ T cells has been associated with decreased survival times for dogs with osteosarcoma.

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
YCATE55.9
Isotype
IgG1

Immunogen

Immunogen
Canine CD8a chimeric human IgG1 Fc fusion protein.
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.