Monoclonal Rat anti-Mouse CD90.2 (Mouse) Antibody (clone 30H12, AF647)
Catalog Number: LS-C810655
2 sizes / from $259.00
Antibody: Rat Monoclonal
Applications: Flow Cytometry
Reactivity: Mouse
Format: Liquid
Monoclonal Mouse MLH1 Antibody (clone G168-15, IHC)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Hamster, Human, Rat |
| Format: | Liquid |
$289.00each
Catalog Number: LS-C95607-0.1
Catalog Number: LS-C95607
For bulk orders or custom formulations:
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- Description
- MLH1 antibody LS-C95607 is an unconjugated mouse monoclonal antibody to MLH1 from human, rat and hamster. Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Ham, Hu, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- COCA2 | FCC2 | HMLH1 | HNPCC | HNPCC2 | MLH1 | MutL protein homolog 1
- UniProt Number
- P40692
- NCBI GenBank
- NM_000249 | NP_000240.1
- SwissProt
- P40692
Target
- Target
- MLH1
- Epitope
- The G168-15 antibody recognizes the human and mouse MLH1 (80-85kDa. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair. cross reacts with human, hamster and rat
- Gene Name
- MLH1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- G168-15
- Isotype
- IgG1
- Origin Species
- Human
Immunogen
- Immunogen
- Full length recombinant MLH.
- Immunogen Type
- Full-Length Recombinant Protein
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Supplied as a liquid containing sodium azide as a preservative
- Volume
- 0.1 Milliliter
- Preservative
- Yes
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C. Do not freeze.
