LSBio
Monoclonal Mouse anti-Synthetic Nitrotyrosine Antibody (clone 6B2-3G2, WB)

Monoclonal Mouse anti-Synthetic Nitrotyrosine Antibody (clone 6B2-3G2, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunoprecipitation, Western Blot
Reactivity:Other
Format:Liquid
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$415.00each
Catalog Number: LS-C188597-0.1

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Overview

Description
Nitrotyrosine antibody LS-C188597 is an unconjugated mouse monoclonal antibody to synthetic Nitrotyrosine. Validated for ELISA, IP and WB.
Application
ELISA, IP, WB
Reactivity
Other
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies

Target

Target
Synthetic Nitrotyrosine
Antigen Species
Other
Epitope
Recognizes both free and protein-bound nitrotyrosine (Tyr-NO2), including human serum nitro albumin, nitro insulin and nitro haemoglobin. Nitrotyrosine arises from the nitration of protein tyrosine residues, by reactive nitrogen species such as peroxynitrite and nitrogen dioxide, and can be used as a measure of NO-dependent oxidative stress and cell damage. Increased levels of nitrotyrosine are detectable in various pathological conditions including atherosclerosis, rheumatoid arthritis, cardiovascular disease, lung cancer and vasculitis. The specificity of the antibody as determined by competition ELISA is: Nitrotyrosine:95 % of inhibition; Tyrosine:0 % of inhibition; Nitrotryptophan:4 % of inhibition; Aminotyrosine:0 % of inhibition; Phosphotyrosine:2 % of inhibition; Chlorotyrosine:3 % of inhibition;.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
6B2-3G2
Isotype
IgG1

Immunogen

Immunogen
Protein-bound Nitrotyrosine.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.