LSBio
Monoclonal Mouse anti-Mouse CD66a / CEACAM1 Antibody (clone CC1, IHC)

Monoclonal Mouse anti-Mouse CD66a / CEACAM1 Antibody (clone CC1, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Mouse
Format:Liquid
See all Mouse CD66a / CEACAM1 antibodies →
$294.00each
Catalog Number: LS-C106710-25

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Overview

Description
CEACAM1 antibody LS-C106710 is an unconjugated mouse monoclonal antibody to mouse CEACAM1 (CD66a). Validated for Flow and IHC. Cited in 4 publications.
Application
FC, IHC, IHC-P
Reactivity
Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Antigen CD66 | BGP1 | Biliary glycoprotein 1 | CD66a | BGP-1 | CEACAM1 | BGP | BGPI | CD66a antigen
UniProt Number
P13688
SwissProt
P13688

Target

Target
Mouse CD66a / CEACAM1
Antigen Species
Mouse
Gene Name
CEACAM1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
CC1
Isotype
IgG1

Immunogen

Immunogen
Purified brush border membranes from BALB/c mice
Immunogen Type
Native Protein (Purified from Natural Source)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Aqueous buffer, 0.09% sodium azide, contains stabilizer if necessary
Concentration
0.5 mg/mL
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C, avoid freeze-thaw cycles.

Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Carpentier R, Su[Character f1]er RE, van Hul N, Kopp JL, Beaudry JB, Cordi S, Antoniou A, Raynaud P, Lepreux S, Jacquemin P, Leclercq IA, Sander M, Lemaigre FP. Gastroenterology. 2011 Oct;141:1432-8, 1438.e1-4.

PubMed: 21708104 · PMC: PMC3494970


Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice. Espa[Character f1]ol-Su[Character f1]er R, Carpentier R, Van Hul N, Legry V, Achouri Y, Cordi S, Jacquemin P, Lemaigre F, Leclercq IA. Gastroenterology. 2012 Dec;143:1564-1575.e7.

PubMed: 22922013


Invasive Ductular Reaction Operates Hepatobiliary Junctions upon Hepatocellular Injury in Rodents and Humans. Clerbaux LA, Manco R, Van Hul N, Bouzin C, Sciarra A, Sempoux C, Theise ND, Leclercq IA. The American journal of pathology. 2019 August;189:1569-1581.

PubMed: 31108103


Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors10<sup> Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, PA, USA12<sup> Center for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA, USA; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA14<sup> Division of Gastroenterology, Hepatology, and N. Laura M Molina, Junjie Zhu, Qin Li, Tirthadipa Pradhan-Sundd, Yekaterina Krutsenko, Khaled Sayed, Nathaniel Jenkins, Ravi Vats, Bharat Bhushan, Sungjin Ko, Shikai Hu, Minakshi Poddar, Sucha Singh, Junyan Tao, Prithu Sundd, Aatur Singhi, Simon Watkins, Xiaochao Ma, Panayiotis V Benos, Andrew Feranchak, George Michalopoulos, Kari Nejak-Bowen, Alan Watson, Aaron Bell, Satdarshan P Monga. Cell reports. 2021 Jul;36:109310.

PubMed: 34233187 · PMC: PMC8280534

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