LSBio
Monoclonal Mouse anti-Human TLR4 Antibody (clone HTA125, RPE)

Monoclonal Mouse anti-Human TLR4 Antibody (clone HTA125, RPE)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry
Reactivity:Human
Format:Lyophilized
See all Human TLR4 antibodies →
$413.00each
Catalog Number: LS-C44227-100

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Overview

Description
TLR4 antibody LS-C44227 is an RPE-conjugated mouse monoclonal antibody to human TLR4. Validated for Flow.
Application
FC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD284 | CD284 antigen | Homolog of Drosophila toll | TLR-4 | TOLL | ARMD10 | TLR4 | Toll-like receptor 4 | HToll
UniProt Number
O00206
NCBI GenBank
NM_138554
SwissProt
O00206
Recommended Dilution
ApplicationDilution
FC1:1

Target

Target
Human TLR4
Antigen Species
Human
Epitope
Recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. Has been demonstrated to block activation of monocytes with LPS. XXX XXX recommend the use of MCA2061EL for this purpose.
Gene Name
TLR4

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
HTA125
Isotype
IgG2a

Immunogen

Immunogen
Ba/F3 cell line expressing TLR4 (CD284)
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Phycoerythrin
Format
Lyophilized
Formulation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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