LSBio
Monoclonal Mouse anti-Human p66 / SHC Antibody (N-Terminus, WB)

Monoclonal Mouse anti-Human p66 / SHC Antibody (N-Terminus, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity:Human
Format:Liquid
See all Human p66 / SHC antibodies →
$590.00each
Catalog Number: LS-C10119-50

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Overview

Description
SHC antibody LS-C10119 is an unconjugated mouse monoclonal antibody to human SHC (p66) (N-Terminus). Validated for ELISA and WB. Cited in 2 publications.
Application
ELISA, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
p46 shc | p52 shc | SH2 domain protein C1 | SHC1 | p66 | SHCA | SHC | SHC-transforming protein 1 | SHC-transforming protein 3 | SHC-transforming protein A
UniProt Number
P29353
SwissProt
P29353

Target

Target
Human p66 / SHC
Antigen Species
Human
Epitope
Recognizes the N-terminus of human p66Shc. Species cross-reactivity: mouse, rat and canine.
Gene Name
SHC1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Isotype
IgG1

Immunogen

Immunogen
Synthetic peptide corresponding to a portion of N-Terminus p66Shc.
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.09% sodium azide, PEG, sucrose, 50% glycerol
Concentration
0.1 mg/mL
Preservative
Yes
Purification Method
Other

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy. Xu X, Zhu X, Ma M, Han Y, Hu C, Yuan S, Yang Y, Xiao L, Liu F, Kanwar YS, Sun L. Scientific reports. 2016;6:29302.

PubMed: 27377870 · PMC: PMC4932503


The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss. A R Fetoni, S L M Eramo, F Paciello, R Rolesi, D Samengo, G Paludetti, D Troiani, G Pani. Scientific reports. 2016 May;6:25450.

PubMed: 27157635 · PMC: PMC4860599

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