Monoclonal Rat anti-Mouse CD90.2 (Mouse) Antibody (clone 30H12, AF647)
Catalog Number: LS-C810655
2 sizes / from $259.00
Antibody: Rat Monoclonal
Applications: Flow Cytometry
Reactivity: Mouse
Format: Liquid
Immunohistochemistry of paraffin-embedded normal human colon with Mouse anti-Human MMP-1 after citrate retrieval
Monoclonal Mouse anti-Human MMP1 Antibody (clone 3B6, C-Terminus, IHC, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$415.00each
Catalog Number: LS-C188387-0.2
Catalog Number: LS-C188387
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- Description
- MMP1 antibody LS-C188387 is an unconjugated mouse monoclonal antibody to human MMP1 (C-Terminus). Validated for IHC and WB.
- Application
- IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CLG | Matrix metalloprotease 1 | MMP-1 | MMP1 | Interstitial collagenase | Matrix metalloproteinase 1 | Matrix metalloproteinase-1
- UniProt Number
- P03956
- NCBI GenBank
- NM_002421 | NP_002412.1
- SwissProt
- P03956
Target
- Target
- Human MMP1
- Antigen Species
- Human
- Epitope
- Recognizes human matrix metalloproteinase 1 (MMP-1). The MMPs are zinc-dependent endopeptidases responsible for degrading the extracellular matrix. They are also involved in cell proliferation, migration, differentiation and apoptosis. Most MMPs are synthesized as inactive zymogens and a propeptide region must be cleaved off before the enzyme becomes active. Their expression is increased dramatically in a variety of cancer types, where it indicates invasive disease and a poor prognosis. MMP-1 is one of the collagenases, capable of degrading collagens I, II and III, all main components of the interstitial stroma. It is overexpressed in invasive melanoma, colorectal and esophageal cancers. It has also been implicated in arthritis and might influence atherosclerotic lesion formation. It might also be involved in the repair processes of the heart after myocardial infarction.
- Gene Name
- MMP1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 3B6
- Isotype
- IgG1
Immunogen
- Immunogen
- Ovalbumin conjugated synthetic peptide corresponding to a region within the C-Terminus of human MMP-1.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS
