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Monoclonal Mouse anti-Human ITGAX / CD11c Antibody (clone CBR-p150/4G1, Preservative Free, IHC)

Monoclonal Mouse anti-Human ITGAX / CD11c Antibody (clone CBR-p150/4G1, Preservative Free, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunohistochemistry, Frozen
Reactivity:Human
Format:Liquid
See all Human ITGAX / CD11c antibodies →
$581.00each
Catalog Number: LS-C58330-0.1

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Overview

Description
CD11c antibody LS-C58330 is an unconjugated mouse monoclonal antibody to human CD11c (ITGAX). Validated for Flow and IHC.
Application
FC, IHC-F
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD11c antigen | Integrin alpha-X | Leu M5, alpha subunit | p150 95 integrin alpha chain | ITGAX | SLEB6 | CD11C | Leu M5
Recommended Dilution: IHC-F
5 - 10 µg/ml
UniProt Number
P20702
SwissProt
P20702

Target

Target
Human ITGAX / CD11c
Antigen Species
Human
Epitope
Recognizes human CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95, a 150kD type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen. Clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. Does not recognize CD11a, CD11b or CD18.
Gene Name
ITGAX

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
CBR-p150/4G1
Isotype
IgG2a

Immunogen

Immunogen
Recombinant human CD11c.
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS
Concentration
1 mg/mL
Preservative
No
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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