LSBio
Monoclonal Mouse anti-Human IRF5 Antibody (clone 10T1, aa176-240, IHC, WB)

Monoclonal Mouse anti-Human IRF5 Antibody (clone 10T1, aa176-240, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
See all Human IRF5 antibodies →
$451.00each
Catalog Number: LS-C45031-0.1

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Overview

Description
IRF5 antibody LS-C45031 is an unconjugated mouse monoclonal antibody to human IRF5 (aa176-240). Validated for ELISA, IHC, IP and WB.
Application
ELISA, IHC-P, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Interferon regulatory factor 5 | IRF-5 | SLEB10 | IBD14 | IRF5
Recommended Dilution: WB
1:1000 - 1:2000
UniProt Number
Q13568
NCBI GenBank
NM_002200 | NP_116032.1
SwissProt
Q13568

Target

Target
Human IRF5
Antigen Species
Human
Epitope
Recognizes human interferon regulatory factor 5 (IRF5), a 58kD member of the IRF family which acts as a key regulator of interferon gene transcription, and is expressed in B cells and dendritic cells, and is inducible by type I interferon (IFN) in most lymphoid cells. The role of IRF3 and IRF7 as transcriptional mediators of virus- and IFN-induced signaling pathways is well documented. Studies have shown that IRF5 can also regulate IFN gene transcription, but appears to be more restricted in its cellular expression and range of viral stimuli, and has the ability to induce a wide range of chemokines involved in T-lymphocyte recruitment, including RANTES, MCP-1 and IP-10.
Gene Name
IRF5

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
10T1
Isotype
IgG1

Immunogen

Immunogen
Recombinant human IRF5 (176-240aa) purified from E. coli.
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.