LSBio
Monoclonal Mouse anti-Human FXN / Frataxin Antibody (clone 1D9, WB)

Immunoprecipitation of FXN transfected lysate using anti-FXN monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with FXN rabbit polyclonal antibody.

Monoclonal Mouse anti-Human FXN / Frataxin Antibody (clone 1D9, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
See all Human FXN / Frataxin antibodies →
$342.00each
Catalog Number: LS-C197243-100

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Overview

Description
Frataxin antibody LS-C197243 is an unconjugated mouse monoclonal antibody to human Frataxin (FXN). Validated for ELISA, IP and WB. Cited in 3 publications.
Application
ELISA, IHC, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CyaY | Frataxin, mitochondrial | Friedreich ataxia protein | FARR | Friedreich ataxia | FA | FRDA | X25 | Frataxin | FXN
UniProt Number
Q16595
SwissProt
Q16595

Target

Target
Human FXN / Frataxin
Antigen Species
Human
Epitope
Human FXN / Frataxin
Gene Name
FXN

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
1d9
Isotype
IgG1
Light Chain
Kappa Light Chain

Immunogen

Immunogen
FXN (AAH48097.1, aa 91-200). A partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4
Concentration
0.5 mg/mL
Preservative
No
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Characterization of a new N-terminally acetylated extra-mitochondrial isoform of frataxin in human erythrocytes. Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Mesaros C, Lynch DR, Blair IA. Scientific reports. 2018 November;8:17043.

PubMed: 30451920 · PMC: PMC6242848


Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich's Ataxia. Lili Guo, Qingqing Wang, Liwei Weng, Lauren A Hauser, Cassandra J Strawser, Agostinho G Rocha, Andrew Dancis, Clementina Mesaros, David R Lynch, Ian A Blair. Analytical Chemistry. 2018 February;90:2216-2223.

PubMed: 29272104 · PMC: PMC5817373


Evaluation of antibodies for western blot analysis of frataxin protein isoforms. Liwei Weng, Qingqing Wang, Sixiang Yu, Xiaolu Yang, David R Lynch, Clementina Mesaros, Ian A Blair. Journal of immunological methods. 2019 Nov;474:112629.

PubMed: 31279523 · PMC: PMC6829029

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