LSBio
Monoclonal Mouse anti-Human FASLG / Fas Ligand Antibody (clone NOK-1, IF)

Human Fas Ligand transfected cells stained with purified NOK-1, followed by biotinylated anti-mouse IgG and Sav-PE

Monoclonal Mouse anti-Human FASLG / Fas Ligand Antibody (clone NOK-1, IF)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunoprecipitation
Reactivity:Human
Format:Liquid
See all Human FASLG / Fas Ligand antibodies →
$332.00each
Catalog Number: LS-C40984-100

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Overview

Description
Fas Ligand antibody LS-C40984 is an unconjugated mouse monoclonal antibody to human Fas Ligand (FASLG). Validated for Flow, ICC, IF and IP. Cited in 7 publications.
Application
FC, ICC, IF, IHC, IP
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
ALPS1B | Apoptosis antigen ligand | APTL | CD95L | CD95 ligand | CD178 antigen | CD95-L | Fas antigen ligand | Fas ligand | FASL | TNFSF6 | APT1LG1 | CD178 | FASLG
UniProt Number
P48023
SwissProt
P48023

Target

Target
Human FASLG / Fas Ligand
Antigen Species
Human
Epitope
L5178Y mouse T lymphoma cells expressing recombinant human FasL
Gene Name
FASLG

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
NOK-1
Isotype
IgG1

Immunogen

Immunogen
Recombinant human FASLG / FASL.
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
Concentration
0.5 mg/mL
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C. Store undiluted.
Recommended Storage Buffer
Phosphate-buffered

Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis. Strauss L, Bergmann C, Whiteside TL. Journal of immunology (Baltimore, Md. : 1950). 2009;182:1469-80.

PubMed: 19155494


Lipopolysaccharide can trigger a cathepsin B-dependent programmed death response in human endothelial cells. Li JH, D'Alessio A, Pober JS. The American journal of pathology. 2009;175:1124-35.

PubMed: 19661440 · PMC: PMC2731131


Intensive resistance exercise induces lymphocyte apoptosis via cortisol and glucocorticoid receptor-dependent pathways. Krger K, Agnischock S, Lechtermann A, Tiwari S, Mishra M, Pilat C, Wagner A, Tweddell C, Gramlich I, Mooren FC. Journal of applied physiology (Bethesda, Md. : 1985). 2011;110:1226-32.

PubMed: 21393471


Efficient Nef-mediated downmodulation of TCR-CD3 and CD28 is associated with high CD4+ T cell counts in viremic HIV-2 infection. Khalid M, Yu H, Sauter D, Usmani SM, Schmokel J, Feldman J, Gruters RA, van der Ende ME, Geyer M, Rowland-Jones S, Osterhaus AD, Kirchhoff F. Journal of virology. 2012;86:4906-20.

PubMed: 22345473 · PMC: PMC3347365


Phenotypic and functional characterization of human T-cell subsets in response to influenza A viruses. Qin G, Liu Y, Zheng J, Xiang Z, Ng IH, Malik Peiris JS, Lau YL, Tu W. The Journal of infectious diseases. 2012;205:1646-53.

PubMed: 22457284


CD8+ T cells use TRAIL to restrict West Nile virus pathogenesis by controlling infection in neurons. Shrestha B, Pinto AK, Green S, Bosch I, Diamond MS. Journal of virology. 2012;86:8937-48.

PubMed: 22740407 · PMC: PMC3416144


Exercise delays neutrophil apoptosis by a G-CSF-dependent mechanism. Mooren FC, Vlker K, Klocke R, Nikol S, Waltenberger J, Krger K. Journal of applied physiology (Bethesda, Md. : 1985). 2012;113:1082-90.

PubMed: 22858628

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