LSBio
Monoclonal Mouse anti-Human Complement C4d Antibody (clone 057-51.5.1.6, IHC)

Monoclonal Mouse anti-Human Complement C4d Antibody (clone 057-51.5.1.6, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry, Frozen
Reactivity:Human
Format:Liquid
See all Human Complement C4d antibodies →
$540.00each
Catalog Number: LS-C44998-0.1

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Overview

Description
Complement C4d antibody LS-C44998 is an unconjugated mouse monoclonal antibody to human Complement C4d. Validated for ELISA, Flow and IHC.
Application
ELISA, FC, IHC-F
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies

Target

Target
Human Complement C4d
Antigen Species
Human
Epitope
Recognizes a neoantigen on the secreted protein complement component 4d (C4d). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. This requires C4 binding protein or CR1 as a cofactor. iC4b is further degraded into C4d and C4c. The short half life of C4d means that it is present in serum at high enough concentrations to make it a useful marker for classical complement activation. C4 has been linked to susceptibility to systemic lupus erythematosus.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
057-51.5.1.6
Isotype
IgG1

Immunogen

Immunogen
Purified human C4d.
Immunogen Type
Native Protein (Purified from Natural Source)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
BBS, 0.1% Sodium Azide
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
bbs

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.