LSBio
Monoclonal Mouse anti-Human CD79A / CD79 Alpha Antibody (clone HM57, FITC, Cytoplasmic Domain)

Monoclonal Mouse anti-Human CD79A / CD79 Alpha Antibody (clone HM57, FITC, Cytoplasmic Domain)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry
Reactivity:Human
Format:Liquid
See all Human CD79A / CD79 Alpha antibodies →
$335.00each
Catalog Number: LS-C44953-0.1

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Overview

Description
CD79 Alpha antibody LS-C44953 is an FITC-conjugated mouse monoclonal antibody to human CD79 Alpha (CD79A) (Cytoplasmic Domain). Validated for Flow. Cited in 2 publications.
Application
FC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD79a antigen | CD79A | Ig-alpha | MB-1 | MB-1 membrane glycoprotein | Surface IgM-associated protein | MB1
Recommended Dilution: FC
1:1 - 1:5
UniProt Number
P11912
SwissProt
P11912

Target

Target
Human CD79A / CD79 Alpha
Antigen Species
Human
Epitope
Recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin
Gene Name
CD79A

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
HM57
Isotype
IgG1

Immunogen

Immunogen
Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Fluorescein Isothiocyanate
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide, 1% BSA
Concentration
0.1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

Broad feedback inhibition of pre-B-cell receptor signaling components. Hauser J, Verma-Gaur J, Grundstr[Character f6]m T. Molecular immunology. 2013 Jul;54:247-53.

PubMed: 23318223


Negative feedback regulation of antigen receptors through calmodulin inhibition of E2A. Verma-Gaur J, Hauser J, Grundström T. Journal of immunology (Baltimore, Md. : 1950). 2012;188:6175-83.

PubMed: 22581853

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