LSBio
Monoclonal Mouse anti-Human CD47 Antibody (clone 1/1A4, IHC)

Monoclonal Mouse anti-Human CD47 Antibody (clone 1/1A4, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunoprecipitation
Reactivity:Human
Format:Liquid
See all Human CD47 antibodies →
$392.00each
Catalog Number: LS-C188327-0.2

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Overview

Description
CD47 antibody LS-C188327 is an unconjugated mouse monoclonal antibody to human CD47. Validated for Flow, IHC and IP.
Application
FC, IHC, IHC-F, IP
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD47 antigen | CD47 molecule | CD47 | Integrin associated protein | Integrin-associated protein | Leukocyte surface antigen CD47 | MER6 | Protein MER6 | Rh-related antigen | OA3 | CD47 glycoprotein | IAP
Recommended Dilution: FC
1:25 - 1:100
UniProt Number
Q08722
SwissProt
Q08722

Target

Target
Human CD47
Antigen Species
Human
Epitope
Specific for human CD47, also known as integrin-associated protein, a 50kD glycoprotein expressed on all hematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1. Cross-linking of CD47 with clone 1/1A4 co-stimulates the proliferation of T cells.
Gene Name
CD47

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
1/1A4
Isotype
IgG2b

Immunogen

Immunogen
Human erythrocytes.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.