LSBio
Monoclonal Mouse anti-Human ACAN / Aggrecan Antibody (clone 7D4, IHC, WB)

Recombinant human aggrecan detected with Mouse anti-Human Aggrecan followed by Goat anti-Mouse IgG:Dylight800. Visualized using a LI-COR Odyssey infrared imaging system

Monoclonal Mouse anti-Human ACAN / Aggrecan Antibody (clone 7D4, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
See all Human ACAN / Aggrecan antibodies →
$455.00each
Catalog Number: LS-C187469-0.2

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Overview

Description
Aggrecan antibody LS-C187469 is an unconjugated mouse monoclonal antibody to human Aggrecan (ACAN). Validated for ELISA, IHC, IP and WB.
Application
ELISA, IHC, IHC-F, IHC-P, IP, WB
Reactivity
Hu
Nonreactive Species
Chicken, Rat
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
AGCAN | Aggrecan core protein | Acg1 | Aggrecan | CSPG1 | CSPGCP | CSPCP | ACAN | AGC1 | Aggrecan 1 | Large aggregating proteoglycan | MSK16 | SEDK | MCSPG
UniProt Number
P16112
NCBI GenBank
NM_013227 | NP_037359.3
SwissProt
P16112

Target

Target
Human ACAN / Aggrecan
Antigen Species
Human
Epitope
Recognizes human aggrecan, a proteoglycan and member of the aggrecan/versican proteoglycan family, which forms a major component of the extracellular matrix (ECM) of both cartilage and the central nervous system (CNS). Studies using a panel of core protein-directed antibodies against human aggrecan, revealed the distribution of different aggrecan isoforms within the CNS, and sub-divided the isoforms into clusters 1-5 accordingly. These studies also showed a difference in the relative abundance of these isoforms when comparing brain and cartilage tissues. recognizes epitopes within the N-terminal G1-IGD-G2 region of aggrecan, that has been identified as a cluster 1 isoform.
Gene Name
ACAN

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
7D4
Isotype
IgG1

Immunogen

Immunogen
Purified human articular cartilage aggrecan.
Immunogen Type
Native Protein (Purified from Natural Source)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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