Formalin-fixed, paraffin-embedded human spleen stained with MMP9 Rabbit Recombinant Monoclonal Antibody (MMP9/2025R).
MMP9 / Gelatinase B Antibody (aa 603-614, clone MMP9/2025R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751270-20
Catalog Number: LS-C751270
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- Description
- Gelatinase B antibody LS-C751270 is an unconjugated rabbit recombinant monoclonal antibody to human Gelatinase B (MMP9) (aa 603-614). Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- 92kd gelatinase | 92 kDa gelatinase | Matrix metalloproteinase-9 | MMP9 | MMP-9 | CLG4B | Gelatinase B | GELB | Macrophage gelatinase | MANDP2
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P14780
- NCBI GenBank
- NM_004994 | NP_004985.2
- SwissProt
- P14780
Target
- Target
- Human MMP9 / Gelatinase B
- Antigen Species
- Human
- Epitope
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is down-regulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.
- Gene Name
- MMP9
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- MMP9/2025R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant fragment (around aa 603-614) of human MMP-9 protein. Antigen Molecular Weight: 92 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS