Formalin-fixed, paraffin-embedded Human Melanoma stained with MART-1 Rabbit Recombinant Monoclonal Antibody (MLANA/1761R) (AP-Fast Red).
MLANA / Melan-A Antibody (clone MLANA/1761R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751137-100
Catalog Number: LS-C751137
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- Description
- Melan-A antibody LS-C751137 is an unconjugated rabbit recombinant monoclonal antibody to human Melan-A (MLANA). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- Antigen LB39-AA | Antigen SK29-AA | Melan-A | MLANA | Protein Melan-A | MART-1 | MART1 | Melan A
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- Q16655
- NCBI GenBank
- NM_005511 | NP_005502.1
- SwissProt
- Q16655
Target
- Target
- Human MLANA / Melan-A
- Antigen Species
- Human
- Epitope
- This antibody recognizes a protein doublet of 20-22 kDa , identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
- Gene Name
- MLANA
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- MLANA/1761R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length hMART-1 protein. Antigen Molecular Weight: 20-22 kDa (doublet)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS