MICA/B Antibody (clone 6D4, Low Endotoxin)

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Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry, Frozen, Immunoprecipitation
Reactivity:	Human
Format:	Liquid

$654.00each

Catalog Number: LS-C44799-0.5

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Description: B antibody LS-C44799 is an unconjugated mouse monoclonal antibody to human B (MICA). Validated for Flow, IHC and IP.
Application: FC, IHC-F, IP
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Recommended Dilution: IHC-F: 1:100

Target: Human MICA/B
Antigen Species: Human
Epitope: Specific for nonclassical MHC class I chain A (MICA) and nonclassical MHC class I chain MICB (MICB). MICA and MICB are stress inducible antigens, which are closely related and appear functionally indistinguishable. MICA and MICB are ligands for NKG2D, an activating receptor on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. MICA is principally expressed on intestinal epithelium, and several epithelial tumors. Expression may be induced to high surface levels by heat shock, oxidative stress, and virus infection. Clone 6D4 is reported to inhibit the cytotoxicity of NK cells stimulated by IFN alpha-treated dendritic cells.

Storage Conditions: Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS