Positive WB detected in:Hela whole cell lysate,HepG2 whole cell lysate,Mouse stomach tissue;All lanes: MDM4 antibody at 3ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 55,15,14,19,50 kDa;Observed band size: 55 kDa;
MDM4 / MDMX Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C499304-50
Catalog Number: LS-C499304
For bulk orders or custom formulations:
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- Description
- MDMX antibody LS-C499304 is an unconjugated rabbit polyclonal antibody to MDMX (MDM4) from human. It is reactive with human and mouse. Validated for ELISA and WB.
- Application
- ELISA, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Mdm2-like p53-binding protein | MDM4 | MDMX | HDMX | MRP1 | p53-binding protein Mdm4 | Protein Mdm4 | Double minute 4 protein | MDM4-related protein 1 | Protein Mdmx
- UniProt Number
- O15151
- NCBI GenBank
- NM_002393 | NP_002384.2
- SwissProt
- O15151
Target
- Target
- Human MDM4 / MDMX
- Antigen Species
- Human
- Epitope
- Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
- Gene Name
- MDM4
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Protein Mdm4 protein (208-306AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS