Formalin-fixed, paraffin-embedded Human Prostate Carcinoma stained with Galectin-1 Rabbit Recombinant Monoclonal Antibody (GAL1/2499R).
LGALS1 / Galectin 1 Antibody (aa12-108, clone GAL1/2499R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751248-20
Catalog Number: LS-C751248
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- Description
- Galectin 1 antibody LS-C751248 is an unconjugated rabbit recombinant monoclonal antibody to human Galectin 1 (LGALS1) (aa12-108). Validated for ELISA and IHC.
- Application
- ELISA, IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- 14 kDa lectin | 14 kDa laminin-binding protein | 14 kd lectin | GAL1 | Galectin 1 | Galectin-1 | HBL | Lactose-binding lectin 1 | LGALS1 | Galaptin | GBP | HLBP14 | HPL | S-Lac lectin 1 | Gal-1
- Recommended Dilution: ELISA
- 2 - 4 ug/ml
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P09382
- NCBI GenBank
- NM_002305 | NP_002296.1
- SwissProt
- P09382
Target
- Target
- Human LGALS1 / Galectin 1
- Antigen Species
- Human
- Epitope
- Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
- Gene Name
- LGALS1
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- GAL1/2499R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant human Galectin-1 protein fragment (aa12-108). Antigen Molecular Weight: 14 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS