LAG3 Antibody (clone C9B7W)

Primary AntibodyLSBio Guarantee

Antibody:	Rat Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry (general)
Reactivity:	Mouse
Format:	Liquid

$286.00each

Catalog Number: LS-C44774-0.1

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Description: LAG3 antibody LS-C44774 is an unconjugated rat monoclonal antibody to mouse LAG3. Validated for Flow.
Application: FC, IHC
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD223 antigen | LAG-3 | Protein FDC | CD223 | FDC | LAG3 | Lymphocyte-activation gene 3
Recommended Dilution: FC: 1:50 - 1:200
UniProt Number: P18627
NCBI GenBank: NM_002286
SwissProt: P18627

Target: Mouse LAG3
Antigen Species: Mouse
Epitope: Recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II. XXX recommend the use of MCA2386EL for this purpose.
Gene Name: LAG3

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS