Formalin-fixed, paraffin-embedded human Skin stained with Pan-Cytokeratin Recombinant Rabbit Monoclonal Antibody (KRTH/1576R + KRTL/1577R).
KRT76 + KRT77 Antibody (clone KRTH/1576R + KRTL/1577R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751074-20
Catalog Number: LS-C751074
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- Description
- KRT76 + KRT77 antibody LS-C751074 is an unconjugated rabbit recombinant monoclonal antibody to human KRT76 + KRT77. Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Recommended Dilution: IHC-P
- 0.25 - 0.5 µg/ml
Target
- Target
- Human KRT76 + KRT77
- Antigen Species
- Human
- Epitope
- Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1) - 64 kDa (CK3) - 59 kDa (CK4) - 58 kDa (CK5) - 56 kDa (CK6) - 52 kDa (CK8) - 56.5 kDa (CK10) - 50 kDa (CK14) - 50 kDa (CK15) - 48 kDa (CK16) - 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- KRTH/1576R + KRTL/1577R
- Isotype
- IgG1
- Light Chain
- Kappa Light Chain
Immunogen
- Immunogen
- Recombinant full-length human KRT76 and KRT77 proteins. Antigen Molecular Weight: 40-67 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS