Formalin-fixed, paraffin-embedded human Skin stained with Cytokeratin 10 Rabbit Recombinant Monoclonal Antibody (KRT10/1990R).
KRT10 / CK10 / Cytokeratin 10 Antibody (clone KRT10/1990R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751231-100
Catalog Number: LS-C751231
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- Description
- Cytokeratin 10 antibody LS-C751231 is an unconjugated rabbit recombinant monoclonal antibody to human Cytokeratin 10 (KRT10 / CK10). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- BIE | BCIE | CK10 | Cytokeratin 10 | Cytokeratin-10 | EHK | Keratin-10 | KPP | KRT10 | Keratin 10 | CK-10 | K10
- Recommended Dilution: IHC-P
- 1 - 2 µg/ml
- UniProt Number
- P13645
- NCBI GenBank
- NM_000421 | NP_000412.3
- SwissProt
- P13645
Target
- Target
- Human KRT10 / CK10 / Cytokeratin 10
- Antigen Species
- Human
- Epitope
- This MAb recognizes a protein of 56.5 kDa , identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
- Gene Name
- KRT10
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- KRT10/1990R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human KRT10 protein. Antigen Molecular Weight: 56.5 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS