Western blot analyses of prekallikrein and its activation products in human plasma.
KLKB1 / Plasma Kallikrein Antibody (clone 13G11)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$700.00each
Catalog Number: LS-C83337-200
Catalog Number: LS-C83337
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- Description
- Plasma Kallikrein antibody LS-C83337 is an unconjugated mouse monoclonal antibody to human Plasma Kallikrein (KLKB1). Validated for ELISA and WB.
- Application
- ELISA, IHC, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Fletcher factor deficiency | Fletcher factor | Kininogenin | Plasma kallikrein | PKK deficiency | Plasma kallikrein heavy chain | PPK | Prekallikrein deficiency | Plasma kallikrein light chain | Plasma prekallikrein | Kallikrein 3 | KLKB1
- UniProt Number
- P03952
- NCBI GenBank
- NM_000892 | NP_000883.2
- SwissProt
- P03952
Target
- Target
- Human KLKB1 / Plasma Kallikrein
- Antigen Species
- Human
- Epitope
- This antibody recognizes two variants of prekallikrein in human plasma, 88kDa and85kDa, and its activation products kallikrein, the complexes formed by kallikrein with itsendogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45kDaprekallikrein/kallikrein fragments. It also recognizes prekallikrein and its activation products inchimpanzee, rhesus, and baboon plasmas. The epitope for this antibody is located on theprekallikrein/kallikrein heavy chain and is involved in the interaction between prekallikrein andfactor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by ~60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
- Gene Name
- KLKB1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 13G11
- Isotype
- IgG1
- Origin Species
- Human
Immunogen
- Immunogen
- Purified human Kallikrien
- Immunogen Type
- Native Protein (Purified from Natural Source)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4
- Concentration
- 1.6 mg/mL
- Preservative
- No
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS